Sophia Liao

Sophia Liao

Digital Portfolio

About Me

Hi, I'm Sophia Liao, a senior at Leland High School and a student researcher at Loyola University Chicago and The Ohio State University.

I have experience in biomedical engineering and immunology research from working in both labs, and I'm interested in exploring the intersection of these fields to drive innovation in healthcare. Currently, I'm exploring the potential of using microcontroller-based systems for medical diagnostics.

Biomedical Engineering Research

Project Setup
Loyola Lab

Student Researcher @ Chen Lab

Loyola University Chicago Department of Engineering  ·  Sept 2024 – Present

  • I built an Arduino Electrocardiogram acquisition device, where I created a low-cost Arduino system measuring heart rate variability.
  • From my experience in the lab, I learned Arduino programming, PCB design using Autodesk Fusion, and Adobe illustrator skills. Outside of researching, I also illustrated scientific figures included on posters published by Loyola University Chicago.
  • I collaborated with the Yu Lab at the Life Sciences Department, where I contributed to collecting mouse embryo samples for tinnitus research purposes.

2026 IEEE International Electro/Information Technology (EIT) Conference

3rd Place Overall Paper  ·  Engineering Education Technical Session

At the IEEE International Electro/Information Technology (EIT) Conference, I presented my research on a low-cost, Arduino-based electrocardiogram (ECG) acquisition device developed with the Chen Lab at Loyola University Chicago. The system validates the microcontroller's ability to measures heart rate variability using the Root Mean Square of Successive Differences (RMSSD) as a metric, demonstrating how accessible microcontroller-based systems can be applied to medical diagnostics and engineering education.

My work was recognized with the 3rd place overall paper award out of 110+ conference papers and 200+ submissions, and presented in the Engineering Education technical session. Presenting at EIT gave me the opportunity to share my research with the broader engineering community, receive feedback from experts in the field, and connect with other researchers exploring the intersection of engineering and healthcare.

Immunology Research

Lab Session
Buckeye Stadium

Student Researcher @ Huang Lab

The Ohio State University Comprehensive Cancer Center  ·  July 2025 – Aug 2025

  • I worked as a lab assistant at The Ohio State University Comprehensive Cancer Center, where I assisted in research on pancreatic and ovarian cancer. I used various lab techniques in my research, including Polymerase Chain Reaction (PCR) and gel electrophoresis. I was able to analyze tumors through these techniques to see how the mice responded to treatment.
  • At the lab, I was able to get hands-on experience with handling mice and dissecting them to collect bone marrow samples for genotyping.
  • I maintained mouse colonies through daily husbandry including feeding, monitoring health, assisting with breeding, and humane euthanasia in accordance with institutional protocols.
  • Outside of handling lab animals, I also assisted in various laboratory procedures, such as sterilizing equipment, data collection, and organizing lab supplies.

Beyond the Lab

Debate

Policy Debate

  • As the captain of my school's policy debate team, I led my team to compete at various regional and national competitions.
  • I qualified to the 2026 California State Tournament, where I placed in the top 16. I also qualified to the 2026 National Speech and Debate Tournament, where I placed 47th.
  • In preparation for competitions, I guide my team through debate strategy, create and teach lesson plans, and customize materials for 20+ members of my team. My favorite part of debate is the discussion and collaboration that comes with it.
Hiking

Exploring

  • I frequently hike in the Redwood forests and around Half Moon Bay. My favorite trail near me is the Henry Cowell Redwoods State Park due to its accessibility; I love hiking with my relatives to catch up and enjoy the scenery.
  • I'm open to recommendations for new trails or destinations, especially if they're in the Bay Area!